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OBJECTIVE: To determine whether adrenomedullin levels in amniotic fluid were associated with preterm labor.
METHODS: We measured immunoreactive adrenomedullin in amniotic fluid collected by amniocentesis from 36 women with clinical diagnosis of preterm labor or preterm premature rupture of membranes (PROM) and from 18 normal pregnant women.
RESULTS: Amniotic fluid from cases of PROM and failure to respond to tocolysis were associated significantly with higher amniotic fluid adrenomedullin concentrations (177.0 +/- 22.5 pg/mL and 182.7 +/- 22.0 pg/mL, respectively, P
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Amniotic fluid concentrations of adrenomedullin in preterm labor.
Marinoni E et al., 1999
Marinoni E, Di Iorio R, Letizia C, Villaccio B, Alberini A, Cosmi EV
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