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An improved delivery method to achieve sustained physiological P levels would be useful. Based on this single-dose pharmacokinetic study, micronized P prepared in a nonliquefying vaginal cream holds promise as a convenient method to achieve this goal with a single daily application.

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Absorption of micronized progesterone from a nonliquefying vaginal cream.

Kimzey LM et al., 1991

Kimzey LM, Gumowski J, Merriam GR, Grimes GJ Jr, Nelson LM

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